On the Brain

“Monday Musings”, for Monday September 19, 2016
Volume V!, No. 238/298

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The Mysterious Organ: The Brain

by Assad Meymandi, MD, PhD, ScD (Hon), DLFAPA*

This article is designed to elevate awareness of the brain, not just as an organ of mentation, perception, cognition and memory but as a marvelous, even mysterious, complex structure. This structure being responsible for our rich repertoire of feelings such as anger, jealousy, hatred, love, fear, hostility, sadness, compassion, generosity, kindness, guilt, pleasure, altruism, peace and joy.

Traditionally, science has been more concerned with understanding mechanisms than with appreciating personal meanings. However, to understand the brain in totality, we must pay attention to both. As a consequence of this attention, we have learned that the brain is also responsible for our complex spiritual and cosmological pursuits. Scholarship and literature about the brain have expanded rapidly, thanks to a federally funded, $2 billion-per-year research effort organized by Congress that led the 1990’s to be dubbed “The Decade of the Brain.” Mind/brain exploration has also been driven by advances in basic knowledge and by new imaging and biochemical technology. This knowledge and technology allow scientists to watch the brain as it orchestrates the functions of life. Here are a few considerations.

When an outfielder leaps up to snag a fly ball, we admire the ballet-like performance and ponder it. The moment the ball is hit, the outfielder’s brain begins to receive visual inputs. The eye tracks the ball; the brain computes its trajectory. Within milliseconds, millions of instructions are flashed to hundreds of muscles, telling each the exact degree of tension or relaxation required to move the body to the spot where the ball will descend. A flood of signals feeds back to the brain indicating whether each muscle is responding correctly. Finally, in a flurry of rapid-fire calculations that would outstrip the most powerful computer, brain orders muscles to propel the body upward and extend the arm. Gloved hand and baseball arrive at exactly the same point at the same time.

On the other hand, take the case of Rajang Srinivasen Mahadevan, a native of Mangalore, India, who manages to remember the first 31,811 digits of the number pi. This feat is achieved through the function of hippocampus and amygdala, two anatomically small portions of the limbic system and nucleus coeruleus. What part of the brain is responsible for the sudden and overwhelming feelings of warmth and spirituality that sweep one’s soul when listening to a favorite composer? Does the brain contain the soul? What goes wrong with the dopamine and acetylcholine neurotransmitting systems in the brain of an Alzheimer’s patient with no memory, feelings or personality, producing the unwelcome transformation of a person into a human object? What happens to the brain’s indoleamine and serotonin system in clinically depressed patients whose pain of living is so great that makes death a welcome opportunity to end the suffering? What about the ascetic dervish who fasts for 40 days and finds ecstasy in solitude and meditation? And what goes on in the brain of the violinist Medori, (she has performed in Meymandi Concert Hall of Raleigh, home of the North Carolina Symphony) who at age six was able to play classical music without looking at the notes? These are but a few examples of the myriad secrets of this three-pound organ we call the “brain.”

The spin-off of the “Decade of the Brain” is a better understanding of its role in healing, spirituality and wellness. For example, meditation has been shown to enhance healing. The neurophysiology of meditation has been worked out since in studies from London’s Maudsley Hospital, Sweden’s Karolinska Institutet, New York’s Columbia Hospital, and the National Institute of Mental Health. Those studies have demonstrated that meditating for 20 minutes, morning and night, decreases oxygen consumption and the heart rate below that found in sleep. It also increases the blood flow to muscles and organs, decreasing the level of lactic acid and low-density lipoproteins. The brain contains 100 billion neurons, 900 billion glial cells, 100 trillion branches and 1000 trillion receptors. Stewardship of this precious organ—the brain—is a moral responsibility. Tobacco, alcohol, unauthorized drugs and stress are all enemies of our brain. We should avoid them.

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*The writer is Adjunct Professor of Psychiatry, University of North Carolina School of Medicine at Chapel Hill, Distinguished Life fellow American Psychiatric Association; Life Member, American Medical Association; Life Member, Southern Medical Association; and Founding Editor and Editor-in-Chief, Wake County Physician Magazine (1995-2012). He is a Raleigh, North Carolina writer and dramaturge, and the 2016 winner of NC Award in Fine Arts.
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